1,2,3,4-Tetrahydro Staurosporin

Overview

1,2,3,4-Tetrahydrostaurosporine is a derivative of Staurosporine ( HY-15141 ) and an inhibitor of mutant EGFR ( IC 50 =74 nM for EGFRT790M). It is selective for EGFRT790M over wild-type EGFR ( IC 50 =390 nM). It also binds to Janus kinase 3 ( JAK3 ).

Application

Products | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Others | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > JAK

Product Information

• Catalog No.: HY-W740378
• CAS No.: 220038-19-7
• Molecular Formula: C₂₈H₃₀N₄O₃
• Molecular Weight: 470.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source