Melting point	132-135 °C(lit.)
Boiling point	147-148 °C3 mm Hg(lit.)
density	1.109
vapor pressure	0.002Pa at 20℃
refractive index	1.5577 (estimate)
FEMA	4330 | 4-HYDROXYACETOPHENONE
Fp	166 °C
storage temp.	Store below +30°C.
solubility	methanol: 0.1 g/mL, clear
form	Crystalline Powder
pka	8.05(at 25℃)
color	Almost white to beige
Specific Gravity	1.109
Water Solubility	10 g/L (22 ºC)
JECFA Number	2040
BRN	774355
InChIKey	TXFPEBPIARQUIG-UHFFFAOYSA-N
LogP	1.35 at 25℃
CAS DataBase Reference	99-93-4(CAS DataBase Reference)
NIST Chemistry Reference	Acetophenone, 4'-hydroxy-(99-93-4)
EPA Substance Registry System	4-Hydroxyacetophenone (99-93-4)

1-(4-hydroxyphenyl)-ethanon;4’-hydroxy-acetophenon;4-Hydroksyacetofenol;Acetophenone, p-hydroxy-;Ethanone, 1-(4-hydroxyphenyl)-;Hydroxyacetophenone, para;HYDROXYACETOPHENONE-4;HYDROXYBENZOPHENONE-4

p-Hydroxyacetophenone is widely used in medicine, cosmetics and industrial fields. It is a natural plant extract, which naturally exists in the stems and leaves of the Compositae plant, Artemisia annua, the roots of plants such as Artemisia annua, Rhododendron, and Panax ginseng. It has a good effect on yellow eyes caused by diseases such as hepatitis, and also has a good auxiliary effect on yellow eyes caused by various reasons. Due to its weak molecular activity, high temperature resistance, melting point of 95-97 °C and boiling point of 296 °C, it is widely used in various liquid pharmaceuticals and can prolong the shelf life of other active ingredients under high temperature conditions. It has no harm to human skin and is the safest high-temperature auxiliary active stabilizer in the pharmaceutical industry.

4′-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.