• CAS No.:99-93-4
Other grades of this product :

Melting point 132-135 °C(lit.)
Boiling point 147-148 °C3 mm Hg(lit.)
density 1.109
vapor pressure 0.002Pa at 20℃
refractive index 1.5577 (estimate)
Fp 166 °C
storage temp. Store below +30°C.
solubility methanol: 0.1 g/mL, clear
form Crystalline Powder
pka8.05(at 25℃)
color Almost white to beige
Specific Gravity1.109
Water Solubility 10 g/L (22 ºC)
JECFA Number2040
BRN 774355
LogP1.35 at 25℃
CAS DataBase Reference99-93-4(CAS DataBase Reference)
NIST Chemistry ReferenceAcetophenone, 4'-hydroxy-(99-93-4)
EPA Substance Registry System4-Hydroxyacetophenone (99-93-4)
1-(4-hydroxyphenyl)-ethanon;4’-hydroxy-acetophenon;4-Hydroksyacetofenol;Acetophenone, p-hydroxy-;Ethanone, 1-(4-hydroxyphenyl)-;Hydroxyacetophenone, para;HYDROXYACETOPHENONE-4;HYDROXYBENZOPHENONE-4

p-Hydroxyacetophenone is widely used in medicine, cosmetics and industrial fields. It is a natural plant extract, which naturally exists in the stems and leaves of the Compositae plant, Artemisia annua, the roots of plants such as Artemisia annua, Rhododendron, and Panax ginseng. It has a good effect on yellow eyes caused by diseases such as hepatitis, and also has a good auxiliary effect on yellow eyes caused by various reasons. Due to its weak molecular activity, high temperature resistance, melting point of 95-97 °C and boiling point of 296 °C, it is widely used in various liquid pharmaceuticals and can prolong the shelf life of other active ingredients under high temperature conditions. It has no harm to human skin and is the safest high-temperature auxiliary active stabilizer in the pharmaceutical industry.

4′-Hydroxyacetophenone has been used as ketone component in the preparation of 1-aryl-3-phenethylamino-1-propanone hydrochlorides, potential cytotoxic agents, via Mannich reactions.




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