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| PYRIMIDIN-4-YLBORONIC ACID Basic information |
| Product Name: | PYRIMIDIN-4-YLBORONIC ACID | | Synonyms: | PYRIMIDIN-4-YLBORONIC ACID;Pyrimidine-4-boronic acid;PyriMidin-4-boronic acid;Boronic acid,B-4-pyriMidinyl-;Pyrimidine-3-boronic acid;4-Boronopyrimidine;Pyrimidin-4-ylboronic Acid (~80%) | | CAS: | 852362-24-4 | | MF: | C4H5BN2O2 | | MW: | 123.91 | | EINECS: | | Product Categories: | Pyridines | | Mol File: | 852362-24-4.mol |
| PYRIMIDIN-4-YLBORONIC ACID Chemical Properties |
| Melting point | >205°C (dec.) | | Boiling point | 334.7±34.0 °C(Predicted) | | density | 1.33 | | storage temp. | Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.86±0.53(Predicted) | | form | Solid | | color | White to Off-White |
| PYRIMIDIN-4-YLBORONIC ACID Usage And Synthesis |
| Uses | Pyrimidin-4-ylboronic Acid is an intermediate used to prepare aldosterone synthase inhibiting pyrimidinylnaphthalenes via Suzuki cross-coupling reactions. It is also used in the synthesis of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine as a potent, orally active Src kinase inhibitor with antitumor activity. |
| PYRIMIDIN-4-YLBORONIC ACID Preparation Products And Raw materials |
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