Melting point | 183 °C |
Boiling point | 418.73°C (rough estimate) |
density | 0.93 |
vapor density | 13 (vs air) |
refractive index | 1.4155-1.4175 |
Fp | 208.9±23.6 °C |
storage temp. | 2-8°C |
solubility | ethanol: 10 mg/mL |
pka | 8.09(at 25℃) |
form | powder |
Colour Index | 75300 |
color | orange |
Odor | Odorless |
PH Range | Yellow (7.8) to red-brown (9.2) |
Water Solubility | Slightly soluble (hot) |
λmax | 430nm |
Merck | 14,2673 |
Concentration | 1 mCi/ml |
BRN | 2306965 |
Solvent | Ethanol |
Specific Activity | 5-15 Ci/mmol |
Stability: | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
Major Application | Cosmetics, drug-eluting stents, inhibition of formation of skin-wrinkles, treating alzheimer’s disease, skin diseases, coronary restenosis, diabetes, obesity, leukemia, neurofibromas, cancer, antimicrobial, antiviral, antiinflammatory, antiprostate cancer |
InChIKey | VFLDPWHFBUODDF-FCXRPNKRSA-N |
CAS DataBase Reference | 458-37-7(CAS DataBase Reference) |
EPA Substance Registry System | Curcumin (458-37-7) |
Anaturalphenoliccompound.Potentanti-tumoragenthavinganti-inflammatoryandantioxidantproperties.Inducesapoptosisincancercellsandinhibitsphorbolester-inducedproteinkinaseC(PKC)activity.Reportedtoinhibitproductionofinflammatorycytokinesbyperipheralbloodmonocytesandalveolarmacrophages.PotentinhibitorofEGFRtyrosinekinaseandIBkinase.ChemicalbookInhibitsinduciblenitricoxidesynthase(iNOS),cycloxygenaseandlipoxygenase.Easilypenetratesintothecytoplasmofcells,accumulatinginmembranousstructuressuchasplasmamembrane,endoplasmicreticulumandnuclearenvelope.CurcuminiscurrentlybeingexaminedasapossibletherapeuticforthetreatmentofAlzheimersdisease(Chem.andEng.News90(31),44(2012)).
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