Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate
  • CAS No.:88767-98-0
Other grades of this product :
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Basic information
Product Name:Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate
Synonyms:Ethyl (R)-2-hydroxy-4-phenylbutyrate triflate;ethyl (r)-[alpha-(trifluoromethylsulfonyl)oxy]benzenebutanoate;(2R)-2-ethyl-2-hydroxy-4-phenylbutanoic acid;ethyl (r)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate;alpha-[[(Trifluoromethyl)sulfonyl]oxy]-benzenebutanoic acid ethyl ester;(R)-Ethyl-2-trifluoromethyl sulphonyloxy-4-phenyl butanoate;(R)-ethyl 4-phenyl-2-(trifluoromethylsulfonyloxy)butanoate;ethyl (2R)-4-phenyl-2-[(trifluoroMethane)sulfonyloxy]butanoate
CAS:88767-98-0
MF:C13H15F3O5S
MW:340.31
EINECS:1308068-626-2
Product Categories:API intermediates
Mol File:88767-98-0.mol
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Chemical Properties
Boiling point 390.8±42.0 °C(Predicted)
density 1.348
refractive index 1.4520 to 1.4560
storage temp. Sealed in dry,Room Temperature
form clear liquid
color Light yellow to Amber to Dark green
Safety Information
MSDS Information
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Usage And Synthesis
UsesEthyl (R)?-?4-?Phenyl-?2-?[[(trifluoromethyl)?sulfonyl]?oxy]?butyrate is an intermediate in synthesizing Enalapril-d3 Hydrochloride (E555258), which is the hydrochloride salt of Enalapril-d3 (E555253), a labeled version of Enalapril (E555403), an antihypertensive that is also an angiotensin-converting enzyme (ACE) inhibitor.
Ethyl (R)-4-phenyl-2-[[(trifluoromethyl)sulfonyl]oxy]butyrate Preparation Products And Raw materials
Raw materialsEthyl (R)-2-hydroxy-4-phenylbutyrate-->3-Butenoic acid, 2-oxo-4-phenyl-, (E)--->(R)-2-Hydroxy-4-phenylbutyric acid-->Trifluoromethanesulfonic anhydride

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