N-(HYDROXYMETHYL)ACETAMIDE
N-(HYDROXYMETHYL)ACETAMIDE
  • CAS No.:625-51-4
Other grades of this product :
N-(HYDROXYMETHYL)ACETAMIDE Basic information
Product Name:N-(HYDROXYMETHYL)ACETAMIDE
Synonyms:ACETAMIDOMETHANOL;HYDROXYMETHYLACETAMIDE(N-);N-(HYDROXYMETHYL)ACETAMIDE;N-ACETYLMETHANOLAMINE;n-(hydroxymethyl)-acetamid;N-(Hydroxymethyl)acetamide,98+%;Hydroxymethylacetamide;N-(Hydroxymethyl)acetamide,97%
CAS:625-51-4
MF:C3H7NO2
MW:89.09
EINECS:210-897-2
Product Categories:Amino Alcohols;Building Blocks;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
Mol File:625-51-4.mol
N-(HYDROXYMETHYL)ACETAMIDE Chemical Properties
Melting point 48-52 °C
Boiling point 165.17°C (rough estimate)
density 1.14
refractive index 1.4368 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly, Sonicated), DMSO (Slightly), Methanol (Slightly)
pka13.28±0.10(Predicted)
form Crystalline
color White to Off-White Low-Melting
Water Solubility Soluble
Sensitive Hygroscopic
Merck 14,4242
BRN 506226
InChIKeyHWJHZLJIIWOTGZ-UHFFFAOYSA-N
CAS DataBase Reference625-51-4(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS AC3610000
10
HazardClass IRRITANT
HS Code 2928009090
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
N-(HYDROXYMETHYL)ACETAMIDE Usage And Synthesis
Chemical Propertieswhite to light yellow crystalline powder
UsesAntiseptic, disinfectant especially for surgical instruments.
UsesN-(Hydroxymethyl)acetamide (cas# 625-51-4) is used as a catalyst in the method for manufacturing sol-gel silica particles method for manufacturing coating substrate coated with silica particles.
Purification MethodsRecrystallise it from freshly distilled Me2CO, wash the crystals with dry Et2O and dry them in a vacuum desiccator over P2O5. RF 0.4 on paper chromatography with CHCl3/EtOH (2:8) as solvent and developed with ammoniacal AgNO3. It also crystallises in needles from EtOAc containing a few drops of Me2CO. It is hygroscopic and should be stored under dry conditions. [Bachmann et al. J Am Chem Soc 73 2775 1951, Walter et al. Chem Ber 99 3204 1966, Einhorn & Ladisch Justus Liebigs Ann Chem 343 265 1905, Beilstein 2 IV 405.]
N-(HYDROXYMETHYL)ACETAMIDE Preparation Products And Raw materials
Raw materialsGlycylglycine
Preparation ProductsN,N'-methylenediacetamide-->Formaldehyde-->Acetamide

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