| N-ACETYL-L-TYROSINE ETHYL ESTER Basic information |
| Product Name: | N-ACETYL-L-TYROSINE ETHYL ESTER |
| Synonyms: | N-ALPHA-ACETYL-L-TYROSINE ETHYL ESTER;N-ACETYL-L-TYR ETHYL ESTER;N-ACETYL-L-TYROSINE ETHYL ESTER;ethyln-alpha-acetyl-tyrosinate;ATEE;ETHYLACETYL-L-TYROSINE;AC-TYR-OET;AC-TYROSINE-OET |
| CAS: | 840-97-1 |
| MF: | C13H17NO4 |
| MW: | 251.28 |
| EINECS: | 212-663-5 |
| Product Categories: | Amino Acid Ethyl Esters;Amino Acids (C-Protected);Amino Acids;Ac-Amino Acids;Amino Acids (N-Protected);Biochemistry |
| Mol File: | 840-97-1.mol |
| N-ACETYL-L-TYROSINE ETHYL ESTER Chemical Properties |
| Melting point | 78-81 °C |
| Boiling point | 394.43°C (rough estimate) |
| density | 1.1667 (rough estimate) |
| refractive index | 22 ° (C=1, EtOH) |
| storage temp. | Sealed in dry,2-8°C |
| pka | 9.75±0.15(Predicted) |
| Water Solubility | 3.48g/L(28 ºC) |
| CAS DataBase Reference | 840-97-1(CAS DataBase Reference) |
| EPA Substance Registry System | L-Tyrosine, N-acetyl-, ethyl ester (840-97-1) |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| N-ACETYL-L-TYROSINE ETHYL ESTER Usage And Synthesis |
| Enzyme inhibitor | This ester (FW = 251.28 g/mol; Abbreviation ATEE) is a substrate for chymotrypsin that is frequently used in assays of that enzyme. The reaction can be followed by observing the production of free carboxyl groups or by the decrease in absorbance at 237 nm and pH 7. Supersaturated stock solutions (i.e., 10-20 mM) can be prepared by dissolving ATEE in water at 85°C, followed by rapidly cooling to room temperature. These solutions are typically stable for six to twelve hours. N-Acetyl-L-tyrosine ethyl ester inhibits protein-disulfide reductase, glutathione-requiring; thiolsubtilisin; complement component C’. |
| N-ACETYL-L-TYROSINE ETHYL ESTER Preparation Products And Raw materials |
| Raw materials | N-Acetyl-L-tyrosine |
| Preparation Products | Levothyroxine Sodium Impurity 16-->Ethyl L-tyrosinate |
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