Bioactive compounds used in cancer, tumor and oncology research.
Idelalisib-d 5 is a deuterium labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ...
Ritrosulfan is a member of the alkylating sugar alcohol. Ritrosulfan is a hydrolyzing alkylating agent with...
RI(dl)-2 blocks RAD51 ’s D-loop activity in biochemical systems with an IC 50 value of 11.1 µM and inhibits...
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth...
BI-4924 is a lipophilic, highly plasma protein bound selective phosphoglycerate dehydrogenase ( PHGDH ) inhibitor (...
(Rac)-PAT-494 is a type II autotaxin inhibitor with the activity of inhibiting the production of lysophosphatidic...
2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1 and...
Bractoppin is a potent and selective agent-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t)...
TP-008, a chemical probe, is a potent, selective and orally active (Activin-Like Kinase 5) ALK5 inhibitor with pIC...
XR 3054 is an inhibitor for Farnesyl Transferase , that inhibits farnesylation of CAAX recognition peptide with IC...
10-Deazaaminopterin is a potent inhibitor of dihydrofolate reductase . 10-Deazaaminopterin can used in study...
M122 is a potent inhibitor of HDAC1 and HDAC2 , with the IC 50 values of 0.48 μM and 0.47 μM, respectively...
SBP-0636457 (SB1-0636457) is a SMAC mimetic, and as an IAP antagonist. SBP-0636457 binds to the BIR-domains of the...
SEC induces activation of ANXA7 GTPase via the AMPK/mTORC1/STAT3 signaling pathway. SEC selectively promotes...
iJak-381 is a JAK1/2 inhibitor with anti-inflammatory activity. iJak-381 blocks IL-13 signaling and also inhibits...
(S)-C33 is a potent and selective PDE9 (phosphodiesterase-9) inhibitor, with an IC 50 of 11 nM. (S)-C33 can be used...
TNIK-IN-1 (Compound 1) is an inhibitor of Traf2 and Nck-interacting kinase (TNIK), with IC 50 of 65 nM, that has...
Poloppin is a potent, cell penetrant inhibitor of the mitotic Polo-like kinase (PLK) ( IC 50 =26.9 μM) and prevents...
SAR156497 (compound 47) is an Aurora inhibitor, with IC50 values of 0.6 nM and 1 nM for Aurora A and Aurora B...
ZT55 is an orally active and highly-selective JAK2 inhibitor with an IC 50 value of 0.031 μM. ZT55 inhibits the...
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