PROTAC and ADC linkers, drug-linker conjugates and related bioconjugation reagents.
dTRIM24 is a selective bifunctional degrader of TRIM24 based on PROTAC, consists of ligands for von Hippel-Lindau...
N-(Iodoacetamido)-Doxorubicin is an iodine attached Doxorubicin. It can conjugate with molecules containing thiol...
DBCO-PEG4-VA-PBD is a agent-linker conjugate for ADC by using the antitumor antibiotic, Pyrrolobenzodiazepine (PBD)...
Carboxyfluorescein-PEG12-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
dBET1 is a PROTAC compound comprised of BET bromodomain antagonist (+)-JQ1 linked to a cereblon E3 ubiquitin ligase...
Boc-PEG4-Val-Cit-PAB-OH is an enzyme-cleavable ADC linker featuring a Boc-protected amine, a hydrophilic PEG spacer...
(S,R. S)-AHPC-PEG3-acid CAS: 2140807-42-5 Formula: C32H46N4O9S is is a protein degrader builiding block used in the...
PROTAC K-Ras Degrader-4 (Compound 4) is a PROTAC degrader for KRAS that degrades KRAS G12D in GP5d and degrades KRAS...
We can provide high-quality Fmoc-NH-PEG4-CH2CH2COOH and its derived impurities.
Benzyl-PEG3-amine is a PEG linker comprised of a benzyl protecting group and a free amine. Benzyl groups can be used...
(S,R,S)-AHPC-C1-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL...
MC-GGFG-(7ethanol-10NH2-11F-Camptothecin) (compound 141) is a drug-linker conjugates for ADC....
We can provide high-quality Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH and its derived impurities.
dBET57 is a compound that drives the selective degradation of the BRD4 protein. This PROTAC contains JQ1 linked to...
We can provide high-quality MMAF-OMe and its derived impurities.
NEK7 degrader-1 is a NEK7 molecular glue degrader with a DC 50 of 9 nM. NEK7 degrader-1 dose-dependently inhibits...
10-Methoxycamptothecin, a natural derivative of camptothecin from Camptotheca acuminata, exhibits strong anti-cancer...
We can provide high-quality Fmoc-Val-Ala-PAB-OH and its derived impurities.
m-PEG12-DBCO is a long chain click chemistry PEG reagents. The DBCO group can react with azides via a copper-free...
GMB-475 acts as a degrader of BCR-ABL 1 tyrosine kinase and as a recruiter of the E3 ligase Von Hippel Lindau (VHL)...
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