用于肿瘤及相关领域研究的生物活性化合物。
Favipiravir, also known as T-705 or Avigan, is an experimental antiviral drug being developed by Toyama Chemical of...
SEN205A is a fragment compound that binds to the hydrophobic pocket of human S100B ( K d =0.5-1.0 mM), which is the...
golvatinib (also known as E7050) is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor...
VAL-083 is a bi-functional alkylating agent that inhibits U251 and SF188 cell growth in monolayer better than TMZ...
FGFR3-IN-10 is a FGFR3 inhibitor with superior selectivity for FGFR3 over FGFR1 .FGFR3-IN-10 can be used for the...
Acalabrutinib, also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with...
KRAS G12C inhibitor 41 is a potent inhibitor of KRAS G12C . The Ras family of proteins is an important intracellular...
GPS167 is a CLK kinase inhibitor that potently and selectively inhibits recombinant human CLK1 , CLK2 and CLK4 . By...
JR4-187 is an orally active, copper-dependent anticancer agent. JR4-187 downregulates genes involved in oxidative...
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase ( MMP ) inhibitor with IC 50 s of...
AZD-0284 is a selective inverse agonist of the nuclear receptor RORγ . AZD-0284 has the potential for plaque...
FASN-IN-3 is a fatty acid synthase ( FASN ) inhibitor extracted from patent US20170119786A1, compound 242A.
Glycycoumarin is a potent antispasmodic agent. Glycycoumarin is a major bioactive coumarin of licorice and exhibits...
Cyanocobalamin-e-methylamide is a Vitamin B 12 ( HY-B0315 ) analogue. Cyanocobalamin-e-methylamide exerts a plasma...
Withametelin B is a hexacyclic withanolide that can be isolated from Datura metel leaves. Withametelin B can bind to...
KRP-203 monophosphate is a monophosphate of KRP-203 ( HY-13660 ). KRP-203 is an orally active...
S-Geranylgeranyl-L-glutathione is a P2RY8 inhibitor and intercellular signaling molecule that exists endogenously in...
PKM2-IN-8 (Compound 9b) is a pyruvate kinase M2 ( PKM2 ) inhibitor ( IC 50 = 0.31 μM). PKM2-IN-8 has potent...
Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3...
Dovitinib (TKI258) potently inhibited FLT3, c-KIT, FGFR, VEGFR1/2/3, PDGFRß and CSF-1R with IC50 values of 1, 2, 5...
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