Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Eight Chongqing Chemdad Co. ，Ltd

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Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir

CAS No.：198904-86-8

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Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Basic information

Product Name:	Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir
Synonyms:	2-[(2S,3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-hydroxy-4-phenylbutyl] -2-[[4-(2-pyridinyl)phenyl]methyl]hydrazinecarboxylic Acid 1,1-Dimethylethyl Ester;Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir;dimethylethoxy)carbonyl]amino]-2-hydroxy-4-;Hydrazinecarboxylic acid, 2-[(2S,3S)-3-[[(1,1-;phenylbutyl]-2-[[4-(2-pyridinyl)phenyl]methyl]-,1,1-dimethylethyl ester;Hydrazinecarboxylic acid, 2-[(2S,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-4-phenylbutyl]-2-[[4-(2-pyridinyl)phenyl]methyl]-, 1,1-dimethylethyl ester;1-[4-(Pyridin-2-yl)phenyl]-5(S)-2,5-bis[(tert-butyloxycarbonyl)-amino]-4(S)-hydroxyl-6-phenyl-2-azahexane;2-[(2S,3S)-3-[[(1,1-dimethylethoxy)carbonyl]amino]-2-hydroxy-4-phenylbutyl]-2-[[4-(2-pyridi
CAS:	198904-86-8
MF:	C32H42N4O5
MW:	562.7
EINECS:	606-396-7
Product Categories:	Aromatics Compounds;Aromatics;Chiral Reagents;Heterocycles
Mol File:	198904-86-8.mol

Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Chemical Properties

Melting point	185-186℃
density	1.157
vapor pressure	0-0Pa at 25℃
storage temp.	Refrigerator
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
pka	10.05±0.50(Predicted)
form	Solid
color	Off-White to Pale Beige
LogP	3.9 at 30℃ and pH6.9
CAS DataBase Reference	198904-86-8

Safety Information

MSDS Information

Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Usage And Synthesis

Chemical Properties	White Solid
Uses	An intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs
Uses	Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir is an intermediate for the synthesis of Atazanavir (A790051) and the preparation of some peptide analogs.

Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir Preparation Products And Raw materials

Raw materials

Carbamic acid, [(1S,2S)-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2-[(methylsulfonyl)oxy]-1-(phenylmethyl)propyl]-, 1,1-dimethylethyl ester (9CI)-->TERT-BUTYL [(1S,2S)-1-BENZYL-2,3-DIHYDROXYPROPYL]CARBAMATE-->198905-10-1-->198905-08-7-->(2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane-->tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate-->tert-Butyl [[4-(2-pyridinyl)phenyl]methylene]hydrazinecarboxylate-->N-Boc-L-phenylalaninal-->HYDRAZINECARBOXYLIC ACID, [[4-(2-PYRIDINYL)PHENYL]METHYLENE]-, 1,1-DIMETHYLETHYL ESTER-->4-(2-Pyridinyl)benzaldehyde-->4-BROMOBENZALDEHYDE DIMETHYL ACETAL-->2-Bromopyridine-->4-Formylphenylboronic acid-->tert-Butyl carbazate

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