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| GLY-ARG-GLY-ASP-SER Basic information |
| GLY-ARG-GLY-ASP-SER Chemical Properties |
| density | 1.66±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | form | White to off-white lyophilized solid | | pka | 2.85±0.10(Predicted) |
| GLY-ARG-GLY-ASP-SER Usage And Synthesis |
| Uses | Gly-Arg-Gly-Asp-Ser has been used-- as an antigen to determine whether integrin α4 or α5 hinders the adhesion of day 3 postirradiation thymocytes to thymic epithelial cells, in mice
- for the treatment of collagen IV-coated dishes to study the role of integrins α1, αv, β1, and β3 in Sca-1+ progenitor cell differentiation into SMCs (smooth muscle cells)
- as a blocking peptide for the pre-incubation of Nisseria meningitides strains, to perform blocking experiments to study the interactions between these bacterial strains and fibronectin
- for the pre-treatment of EL-4 cells infected by AdCMV-GFP (cytomegalovirus-green fluorescent protein), to study whether interaction with cellular integrins is essential for the transduction of adenovirus
| | General Description | Gly-Arg-Gly-Asp-Ser peptide sequence is identical to the cell-binding region of fibronectin protein. Arg-Gly-Asp (RGD) region is found in various proteins, and is crucial for facilitating cell-adhesive activity. | | Biochem/physiol Actions | Antagonist of integrin function |
| GLY-ARG-GLY-ASP-SER Preparation Products And Raw materials |
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